Open AccessConcurrent nonfunctional paraganglioma of the retroperitoneum and urinary bladder: A case report with literature review
Author(s) -
Poonam Sherwani,
Rama Anand,
MK Narula,
Azaz Akhtar Siddiqui,
Shilpi Aggarwal
Publication year - 2015
Publication title -
indian journal of radiology and imaging
Language(s) - English
Resource type - Journals
eISSN - 0971-3026
pISSN - 0970-2016
DOI - 10.4103/0971-3026.155879
Subject(s) - paraganglioma , medicine , adrenal medulla , histopathology , pheochromocytoma , neuroendocrine tumors , pathology , radiology , catecholamine
Paragangliomas are the neuroendocrine tumors which arise from the chromaffin cell. Tumors arising from the adrenal medulla are known as pheochromocytomas, while others originating from the extra-adrenal site are known as extra-adrenal paragangliomas. Paraganglioma can be multifocal which can arise synchronously or metachronously. Paragangliomas are less functionally active than the pheochromocytomas; they secrete noradrenaline and rarely dopamine, while adrenal pheochromocytomas secrete adrenaline or nor-adrenaline. Nonfunctional multifocal paragangliomas are very rare. We report a case of a 45-year-old female with multifocal nonfunctional paragangliomas of the retroperitoneum and urinarybladder which were surgically removed, and the diagnosis was confirmed on histopathology.