Open AccessFNA diagnosis of CD99 positive neuroblastoma: A diagnostic dilemma
Author(s) -
Gagandeep Kaur,
Pooja Bakshi,
Kusum Verma
Publication year - 2012
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.97162
Subject(s) - cd99 , neuroblastoma , medicine , immunohistochemistry , pathology , differential diagnosis , biology , cell culture , vimentin , genetics
Tissue diagnosis of small round cell tumors relies heavily on immunohistochemical staining. Two of the small round cell tumors, namely neuroblastoma and primitive neuroectodermal tumor, have considerable morphologic overlap. Many studies suggest that CD99 positivity virtually excludes the diagnosis of neuroblastoma. We report a case of poorly differentiated neuroblastoma in which aberrant CD99 positivity led to diagnostic dilemma.