Open AccessCytological features of lung adenocarcinoma with massive lymphocyte infiltration
Author(s) -
F Álvarez-Rodríguez,
Jiménez-Heffernan Ja
Publication year - 2012
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.97159
Subject(s) - pathology , medicine , infiltration (hvac) , neoplasm , adenocarcinoma , lung , stroma , lymphocyte , population , immunology , immunohistochemistry , cancer , physics , environmental health , thermodynamics
Adenocarcinoma with massive lymphocyte infiltration is a rare pulmonary neoplasm with few reported cases. It seems to have a better outcome than conventional adenocarcinomas, but it is still not clear if it constitutes a specific clinicopathological entity. We report a case in which cytological studies were available. The small size of the tumor, abundant lymphocyte population, well-differentiated morphology of the neoplasm and scarcity of atypical cells resulted in a difficult cytological diagnosis. This entity should be considered when evaluating pulmonary lesions with abundant lymphocytes. Not all carcinomas with prominent lymphoid stroma show the high-grade, pleomorphic morphology of lymphoepithelioma-like carcinomas.