Open AccessSignificance of a galactose specific plant lectin for the differential diagnosis of adenocarcinoma cells in effusion
Author(s) -
K. Sujathan,
K Jayasree,
P. Remani
Publication year - 2009
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.62181
Subject(s) - lectin , pathology , glycoconjugate , medicine , adenocarcinoma , malignancy , cytoplasm , cancer research , microbiology and biotechnology , immunology , cancer , biology , biochemistry
Distinguishing adenocarcinoma cells from reactively proliferated mesothelial cells and macrophages is one of the greatest challenges in the cytodiagnosis of effusions. Aberrant glycosylation of cell surface glycoconjugates is emblematic to malignancy, and lectins being an important class of probes to demonstrate these aberrations, lectin cytochemistry is of great interest to differentiate adenocarcinoma cells from reactive mesothelial cells.