Open AccessDiagnosis of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Disease) by fine needle aspiration cytology
Author(s) -
Rashmi Kushwaha,
Charanjeet Ahluwalia,
Varuna Sipayya
Publication year - 2009
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.55229
Subject(s) - rosai–dorfman disease , sinus histiocytosis with massive lymphadenopathy , medicine , cervical lymphadenopathy , lymphoma , fine needle aspiration cytology , etiology , disease , histiocytosis , biopsy , histiocyte , dermatology , pathology , sinus (botany) , radiology , botany , biology , genus
Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a rare benign disease of unknown etiology presenting with massive lymphadenopathy. These cases can often be misdiagnosed as lymphoma. Hence, it is important to distinguish Rosai-Dorfman disease from lymphoma and other causes of histiocytosis because of the different treatment modalities. We report here a case of Rosai-Dorfman presenting with massive bilateral cervical lymphadenopathy. We conclude that fine needle aspiration cytology is a useful and reliable tool for the diagnosis of Rosai-Dorfman disease due to which biopsy can be avoided in these patients, thus, reducing inconvenience to patients.