Open AccessPenicillium marneffei infection in a HIV-Positive patient: A comparison of bronchial washing cytology and biopsy
Author(s) -
Chu Hyun Hee,
Chong Young Pil,
Kyung Ja Cho
Publication year - 2017
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.197618
Subject(s) - medicine , penicillium marneffei , cytology , human immunodeficiency virus (hiv) , biopsy , penicillium , pathology , dermatology , microbiology and biotechnology , immunology , biology , botany , coinfection
Penicilliosis is a disseminated and progressive infection that is mainly found in immunocompromised individuals, especially those with human immunodeficiency virus (HIV) infection. Because of the high mortality of patients with disseminated Penicillium marneffei infection, rapid diagnosis and early treatment are required. Diagnosis is traditionally made by biopsy and/or culture of blood or any involved organ. Cytology offers several advantages over biopsy, including more rapid diagnosis and greater resolution of cytomorphologic details of organisms, allowing rapid initiation of treatment. Here, we describe a case of penicilliosis in an HIV-positive patient with emphasis on the morphological characteristics of the organism in cytologic specimens, as well as a comparison of bronchial washing and biopsy findings.