Open AccessEvaluation of ploidy status using DNA-image cytometry of exfoliated mucosal cells in oral lichen planus
Author(s) -
Ravi Teja Chitturi,
RamdasMadhavan Nirmal,
Paramel Mohan Sunil,
A. Santha Devy,
Baddam Venkat Ramana Reddy
Publication year - 2014
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.145629
Subject(s) - malignancy , medicine , pathology , oral lichen planus , reticular connective tissue , aneuploidy , feulgen stain , ploidy , cytometry , malignant transformation , flow cytometry , gastroenterology , staining , biology , immunology , chromosome , gene , biochemistry
Oral lichen planus (OLP) is one of the potentially malignant disorders (PMDs) with a malignancy rate of 0.2-2%. Aneuploidy is considered to be one of the important markers for malignant transformation and DNA-image cytometry (DIC) has been successfully employed in oral mucosal PMDs and also in tumors of the cervix, lung and biliary tract.