Open AccessLipomatous pleomorphic adenoma in the hard palate: Report of a rare case with cyto-histo correlation and review
Author(s) -
Jamal Musayev,
Binnur Önal,
Adalat Hasanov,
Ismayil Farzaliyev
Publication year - 2014
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.130689
Subject(s) - pleomorphic adenoma , myoepithelial cell , pathology , medicine , mixed tumor , salivary gland , adenoma , lipoma , hard palate , benign tumor , lipomatosis , differential diagnosis , fine needle aspiration , anatomy , biopsy , immunohistochemistry , surgery
Pleomorphic adenoma is the most common benign tumor of the salivary glands. They are usually composed of epithelial/myoepithelial cells and chondromyxoid stroma. Extensive lipomatous differentiation is very rare. We report a case of lipomatous pleomorphic adenoma (LPA) that presented with a mass in the hard palate of a 32-year-old woman. The fine-needle aspiration cytology material was reported as benign cytology consistent with adenoma with major adipocytic component. Histopathological examination of the excision material displayed that more than 90% of the tumor was adipocytic in texture, containing scant epithelial and myoepithelial cells and chondromyxoid stromal fragments. Preoperative cytodiagnosis of lipomatous pleomorphic adenoma on FNA is based on cytomorphology intimately associated pleomorphic adenomatous and lipomatous tissue elements. LPA should be on the mental list of the (cyto)pathologist in differential diagnosis of lipomatous tumors or non-tumorous lipomatosis or carcinoma invasion in the adipose tissue of the minor salivary gland of the hard palate.