Open AccessDemonstration of iron in exfoliated buccal cells of β-thalassemia major patients
Author(s) -
Atul Bhat,
Rajkumar Parwani,
Sangeeta Wanjari
Publication year - 2013
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.117662
Subject(s) - medicine , thalassemia , hemosiderosis , ferritin , gastroenterology , prussian blue , buccal administration , abo blood group system , buccal swab , anemia , pathology , dentistry , microbiology and biotechnology , chemistry , biology , electrode , electrochemistry
Thalassemia is a genetic disorder of hemoglobin synthesis, which requires regular blood transfusion therapy leading to iron overload in the body tissues. Transfusional hemosiderosis is a major cause of morbidity and mortality in these patients. Reliable methods for evaluation of iron overload are either invasive, costly or remotely available. Therefore, a simple technique of monitoring iron overload is desirable.