Open AccessNodular sclerosing adenosis of breast: A diagnostic pitfall in fine needle aspiration cytology
Author(s) -
Sreejesh Sreedharanunni,
Ashim Das,
Veenu Singla,
Radhika Srinivasan,
Gurpreet Singh
Publication year - 2013
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.107514
Subject(s) - medicine , fine needle aspiration , pleomorphism (cytology) , pathology , malignancy , cytology , biopsy , cytopathology , mammography , radiology , breast cancer , immunohistochemistry , cancer
Fine needle aspiration cytology was performed in a 46-year-old female presenting with a breast lump and mammography suggesting a malignancy. The smears were cellular with cohesive clusters and scattered epithelial cells showing moderate nuclear pleomorphism and focal acinar formation. Stromal fragments, benign epithelial cell clusters and a few naked nuclei were noted in the background. Considering the clinical features, mammography findings as well as cytological features, a diagnosis of ductal carcinoma was suggested. Subsequent histopathological examination revealed it to be nodular sclerosing adenosis. The cytohistological correlation of this uncommon lesion, a potential pitfall in breast fine needle aspiration diagnosis which may lead to a false-positive diagnosis is discussed.