The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions | Zendy

LC Alarcón-Romero | Zendy; Ma Isabel Zubillaga-Guerrero | Zendy; Berenice IlladesAguiar | Zendy; Marco Antonio LeyvaVázquez | Zendy; Eugenia FloresAlfaro | Zendy; Eduardo Castañeda-Saucedo | Zendy; Luz del Carmen AlarcónRomero | Zendy

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The integration of HR-HPV increases the expression of cyclins A and E in cytologies with and without low-grade lesions

Author(s) -

LC Alarcón-Romero,

Ma Isabel Zubillaga-Guerrero,

Berenice IlladesAguiar,

Marco Antonio LeyvaVázquez,

Eugenia FloresAlfaro,

Eduardo Castañeda-Saucedo,

Luz del Carmen AlarcónRomero

Publication year - 2013

Publication title -

journal of cytology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.267

H-Index - 19

eISSN - 0974-5165

pISSN - 0970-9371

DOI - 10.4103/0970-9371.107504

Subject(s) - squamous intraepithelial lesion , cyclin , polymerase chain reaction , amplicon , cyclin e , cervical cancer , genotyping , microbiology and biotechnology , cyclin e1 , cell cycle , medicine , cyclin d , biology , pathology , cervical intraepithelial neoplasia , cancer , gene , genetics , genotype

Cyclin-A and cyclin-E are regulators of G1-S phase of normal cell cycle. Integration of human papilloma virus high-risk (HR-HPV) could alter this mechanism, and its overexpression has been associated with poor prognosis in cervical cancer.

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