Open AccessEffectiveness of the cell block technique in diagnostic cytopathology
Author(s) -
Shehnaz Khan,
Omar Touzani,
Pamela Michelow
Publication year - 2012
Publication title -
journal of cytology/journal of cytology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.267
H-Index - 19
eISSN - 0974-5165
pISSN - 0970-9371
DOI - 10.4103/0970-9371.101167
Subject(s) - cytopathology , medicine , immunocytochemistry , pathology , fine needle aspiration , grading (engineering) , staining , histopathology , biopsy , nuclear medicine , cytology , biology , ecology
One of the constraints of the conventional FNA smear is the limited material available for adjuvant diagnostic investigations including immunocytochemistry. The cell block technique employs the retrieval of small tissue fragments from a FNA specimen which are processed to form a paraffin block. It is widely accepted that cell block technique increases the cellular yield and improves diagnostic accuracy. The ability to obtain numerous tissue sections allows for multiple immunostains and other studies to be performed akin to paraffin sections produced in histopathology.