Evaluation of telomerase expression in chronic periodontitis | Zendy

SureshR Rao | Zendy; TM Balaji | Zendy; Vettriselvi Venkatesan | Zendy; Solomon F.D. Paul | Zendy

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Evaluation of telomerase expression in chronic periodontitis

Author(s) -

SureshR Rao,

TM Balaji,

Vettriselvi Venkatesan,

Solomon F.D. Paul

Publication year - 2010

Publication title -

indian journal of dental research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 43

eISSN - 1998-3603

pISSN - 0970-9290

DOI - 10.4103/0970-9290.66632

Subject(s) - chronic periodontitis , telomerase , periodontitis , medicine , telomerase reverse transcriptase , inflammation , polymerase chain reaction , pathogenesis , reverse transcriptase , telomere , aggressive periodontitis , immunology , pathology , gene , biology , genetics

Human telomerase is a multi subunit ribonucleoprotein enzyme concerned with telomeric lengthening and homeostasis in man. This enzyme has been found to be elevated in inflammatory conditions like rheumatoid arthritis and silica injury lung. Since chronic periodontitis is also an inflammatory condition where immune cells and cytokines mediate tissue destruction, we set out to evaluate telomerase in gingival tissue samples from healthy subjects and chronic periodontitis patients by reverse transcriptase polymerase chain reaction.

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