
A rare case of sarcoid-like reaction of lymph nodes associated with squamous cell carcinoma of alveolar mucosa
Author(s) -
Shweta Nag,
TR Saraswathi,
Ganthimathy Sekhar,
A Einstein,
B Sivapathasundharam
Publication year - 2009
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.59446
Subject(s) - sarcoidosis , medicine , pathology , lymph , cervical lymph nodes , etiology , fibrosis , granuloma , cancer , metastasis
Non-necrotizing granulomas are occasionally seen in patients with certain malignant disorders and are termed as "sarcoid-like reaction," which have many similarities with sarcoidosis. Sarcoidosis is a multisystem granulomatous disease of unknown etiology characterized by organ involvement and interference of organ function by granuloma or fibrosis. Sarcoidosis is occasionally found in a variety of malignant diseases with an overall incidence of 4.4% in carcinoma patients. We present here a rare case of moderately differentiated squamous cell carcinoma of alveolar mucosa with regard to mandible associated with sarcoid-like reaction of cervical lymph nodes in a female patient in the absence of clinical evidence of systemic sarcoidosis. The relevant literature including pathogenesis is also discussed.