Open AccessCytotoxicity evaluation of Persica mouthwash on cultured human and mouse cell lines in the presence and absence of fetal calf serum
Author(s) -
Saeed Rajabalian,
Mohammad Ali Mohammadi,
Behrooz Mozaffari
Publication year - 2009
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.52894
Subject(s) - cytotoxicity , cytotoxic t cell , fibroblast , mtt assay , serial dilution , antimicrobial , cell culture , toxicity , microbiology and biotechnology , fetus , chlorhexidine , chemistry , pharmacology , in vitro , traditional medicine , andrology , biology , medicine , biochemistry , pathology , dentistry , pregnancy , genetics , alternative medicine , organic chemistry
The effectiveness of an ideal antimicrobial agent depends on its ability to kill microbes while causing minimal toxicity to host cells. Several studies have been reported on the antimicrobial effects of chewing sticks (Salvadora persica) on oral bacteria. The purpose of this study was to evaluate the cytotoxic effects of Persica and chlorhexidine (CHX) mouthwashes on cultured human and mouse cell lines.