Open AccessExpression of E-cadherin in primary oral squamous cell carcinoma and metastatic lymph nodes: An immunohistochemical study
Author(s) -
Gurkiran Kaur,
Sunitha Carnelio,
Nirmala N Rao,
Laxmi Rao
Publication year - 2009
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.49075
Subject(s) - cadherin , immunohistochemistry , lymph , pathology , metastasis , medicine , cell , carcinoma , biology , cancer , genetics
E-cadherin plays an important role in cell-to-cell adhesion and cell motility and its loss is associated with oral squamous cell carcinoma (OSCC) progression. The aim of this study was to determine the expression of E-cadherin in various grades of OSCC and to correlate changes in the expression between these various grades and metastatic lymph nodes.