Expression of E-cadherin in primary oral squamous cell carcinoma and metastatic lymph nodes: An immunohistochemical study | Zendy

Sunitha Carnelio | Zendy; Gurkiran Kaur | Zendy; Nirmala N Rao | Zendy; Laxmi Rao | Zendy

Open Access

Expression of E-cadherin in primary oral squamous cell carcinoma and metastatic lymph nodes: An immunohistochemical study

Author(s) -

Sunitha Carnelio,

Gurkiran Kaur,

Nirmala N Rao,

Laxmi Rao

Publication year - 2009

Publication title -

indian journal of dental research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.277

H-Index - 43

eISSN - 1998-3603

pISSN - 0970-9290

DOI - 10.4103/0970-9290.49075

Subject(s) - cadherin , immunohistochemistry , lymph , pathology , metastasis , medicine , cell , carcinoma , biology , cancer , genetics

E-cadherin plays an important role in cell-to-cell adhesion and cell motility and its loss is associated with oral squamous cell carcinoma (OSCC) progression. The aim of this study was to determine the expression of E-cadherin in various grades of OSCC and to correlate changes in the expression between these various grades and metastatic lymph nodes.

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