Open AccessGene therapy for oral squamous cell carcinoma: An overview
Author(s) -
TR Saraswathi,
B Kavitha,
Vijayashree Priyadharsini Jayaseelan
Publication year - 2007
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.33787
Subject(s) - genetic enhancement , medicine , basal cell , cancer , cancer research , therapeutic approach , radiation therapy , gene , larynx , oncology , bioinformatics , pathology , biology , surgery , genetics , disease
A potential approach to the treatment of genetic disorders is gene therapy. The goal of gene therapy is to introduce therapeutic genetic material into the target cell to exert the intended therapeutic effect. Gene therapy has already shown promising results for the treatment of monogenic disorders such as severe combined immunodeficiency and haemophilia. Now the procedure has been extended to the level of treating malignant conditions such as cancer of the lungs, breast, colon etc. The prevalence of tumours of the larynx and oral cavity has increased in both developed and developing countries. This increase underscores the need for a novel therapeutic modality that would decrease or completely terminate the proliferation of malignant cells. This review highlights various types of gene therapy procedures with respect to oral squamous cell carcinoma.