Open AccessImmunolocalization of Bcl-2 oncoprotein in amlodipine-induced gingival overgrowth
Author(s) -
Lalitha Tanjore Arunachalam,
Suresh Rao
Publication year - 2013
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.116695
Subject(s) - pathogenesis , amlodipine , immunohistochemistry , basal (medicine) , distribution (mathematics) , medicine , apoptosis , pathology , endocrinology , chemistry , diabetes mellitus , biochemistry , mathematical analysis , mathematics , blood pressure
Drug-induced gingival overgrowth (DIGO) is one of the unwanted side effects of amlodipine therapy, but the pathogenesis still remains unclear. Apoptosis, which plays a ubiquitous role in tissue homeostasis, including gingiva, may be involved in the development of gingival enlargement.