Open AccessImmunohistochemical analysis of CK 18 in dental follicles of impacted third molars: A pilot study
Author(s) -
Anand S Tegginamani,
Rajendra Prasad,
Rekha V. Kumar
Publication year - 2013
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.116671
Subject(s) - dental follicle , immunostaining , pathology , molar , cytokeratin , epithelium , medicine , immunohistochemistry , connective tissue , malignant transformation , maxilla , biology , dentistry , mesenchymal stem cell
Odontogenic tumors are lesions derived from epithelial, ectomesenchymal, and/or mesenchymal elements that still are, or have been, part of the tooth-forming apparatus. Approximately 80% of odontogenic tumors occur in the mandible, with a marked predilection for the posterior region, and are often associated with an unerupted tooth. The aim of this study was to determine whether cytokeratin (CK) 18 immunostaining decorated the follicular tissue removed at the time of prophylactic extraction of impacted mandibular third molars, which might suggest oncofetal transformation.