Open AccessSalivary IgG assay to detect Helicobacter pylori infection in an Indian adult population
Author(s) -
Ramya Thirumala Krishnaswamy,
Chaya M David,
S. Govindaiah,
Ramnarayan Belur Krishnaprasad,
CJ Sanjay
Publication year - 2012
Publication title -
indian journal of dental research/indian journal of dental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.277
H-Index - 43
eISSN - 1998-3603
pISSN - 0970-9290
DOI - 10.4103/0970-9290.107416
Subject(s) - helicobacter pylori , saliva , medicine , serology , chronic gastritis , gastritis , gold standard (test) , gastroenterology , antibody , immunology
Helicobacter pylori infection, the commonest chronic bacterial infection in humans, causes chronic gastritis, peptic ulcer, and possibly gastric carcinoma and lymphoma. Recently, investigators have focused on its role in the development of extra-gastrointestinal diseases with oral manifestations. H. pylori infection can be diagnosed by various methods. Of late, H. pylori IgG antibodies have been detected in saliva using enzyme-linked immunosorbent assay (ELISA). However, local validation of serological test is needed before implementing a test in different populations.