Open AccessMidazolam-induced acute dystonia reversed by diazepam
Author(s) -
Mustafa Kömür,
Ali Ertuğ Arslanköylü,
Çetin Okuyaz
Publication year - 2012
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/0970-9185.98346
Subject(s) - midazolam , medicine , flumazenil , diazepam , dystonia , anesthesia , sedative , benzodiazepine , sedation , psychiatry , receptor
Midazolam can induce acute dystonia in childhood. We report the development of acute dystonia in a 6-year-old girl after receiving midazolam as a sedative. Dystonic contractions persisted despite flumazenil and biperiden lactate injections and the patient was treated with diazepam. Acute dystonia was rapidly abolished after the administration of diazepam intravenously. Diazepam may be an effective treatment option in patients who are unresponsive to flumazenil.