Open AccessHepatic resection is associated with reduced postoperative opioid requirement
Author(s) -
C. Moss,
J. Caldwell,
Babatunde Afilaka,
Khaled Iskandarani,
Ver M. Chinchilli,
Patrick M. McQuillan,
Amanda Cooper,
Niraj J. Gusani,
Dmitri Bezinover
Publication year - 2016
Publication title -
journal of anaesthesiology-clinical pharmacology/journal of anaesthesiology clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.466
H-Index - 32
eISSN - 2231-2730
pISSN - 0970-9185
DOI - 10.4103/0970-9185.188827
Subject(s) - medicine , opioid , resection , anesthesia , surgery , receptor
Postoperative pain can significantly affect surgical outcomes. As opioid metabolism is liver-dependent, any reduction in hepatic volume can lead to increased opioid concentrations in the blood. The hypothesis of this retrospective study was that patients undergoing open hepatic resection would require less opioid for pain management than those undergoing open pancreaticoduodenectomy.