Open AccessDetermination of toral antioxidant capacity of saliva in sickle cell anemic patients – A cross-sectional study
Author(s) -
Sudhindra Baliga,
Minal Chaudhary,
Sham S Bhat,
Poonam Bhatiya,
Nilima Thosar,
Pooja Bhansali
Publication year - 2017
Publication title -
journal of the indian society of pedodontics and preventive dentistry/journal of indian society of pedodontics and preventive dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.378
H-Index - 33
eISSN - 1998-3905
pISSN - 0970-4388
DOI - 10.4103/0970-4388.199219
Subject(s) - saliva , oxidative stress , medicine , anemia , antioxidant , antioxidant capacity , sickle cell anemia , gastroenterology , red cell , physiology , immunology , biochemistry , chemistry , disease
Sickle cell anemia is a congenital hemoglobinopathy characterized by deformed red blood cells. Oxidative stress plays an important role in the pathophysiology of sickle cell anaemia as it destroys free radicals, and thereby depleting the protective mechanisms such as antioxidants in serum. These antioxidants are essential to protect against harmful oxidation-reduction reactions preventing oxidative damage to the cells.