Open AccessFetal hydantoin syndrome: A case report
Author(s) -
Ashish Kumar Singh,
HP Bhatia,
Akhilesh Mohan,
Naresh Kumar Sharma
Publication year - 2016
Publication title -
journal of the indian society of pedodontics and preventive dentistry/journal of indian society of pedodontics and preventive dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.378
H-Index - 33
eISSN - 1998-3905
pISSN - 0970-4388
DOI - 10.4103/0970-4388.175526
Subject(s) - phenytoin , medicine , fetus , hydantoin , pregnancy , teratology , epilepsy , central nervous system , pediatrics , anticonvulsant , intrauterine growth restriction , obstetrics , endocrinology , biology , biochemistry , psychiatry , genetics
Fetal hydantoin syndrome (FHS) is a spectrum of defects caused to the developing fetus by exposure to the teratogenic effects of antiepileptic drug (AED) phenytoin during pregnancy. Its clinical manifestations include limb abnormalities, ocular defects, central nervous system anomalies, intrauterine growth restriction, and hand and phalangeal anomalies. This case report presents an 8-year-old child born to an epileptic mother with a history of AED therapy, with features suggestive of FHS.