Open AccessAdverse drug reactions and treatment outcome analysis of DOTS-plus therapy of MDR-TB patients at district tuberculosis centre: A four year retrospective study
Author(s) -
Arif I Dela,
Nitish Kumar D Tank,
A. P. Singh,
Kiran G Piparva
Publication year - 2017
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.217569
Subject(s) - medicine , discontinuation , tuberculosis , regimen , culture conversion , retrospective cohort study , levofloxacin , adverse effect , extensively drug resistant tuberculosis , pulmonary tuberculosis , antibiotics , mycobacterium tuberculosis , pathology , microbiology and biotechnology , biology
Treatment of multidrug-resistant tuberculosis (MDR-TB) requires the use of expensive and toxic second-line anti-tubercular drugs which are given for a longer duration. Adverse drug reactions (ADRs) of second-line antitubercular drugs affect compliance and thereby treatment outcome. We set out to analyze ADRs and treatment outcome of MDR-TB patients receiving directly observed treatments plus therapy.