Open AccessClinicopathological and immunohistochemical profile of non-small cell lung carcinoma in a tertiary care medical centre in South India
Author(s) -
Shanmugapriya Shankar,
Vijayalakshmi Thanasekaran,
T Dhanasekar,
Prathiba Duvooru
Publication year - 2014
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.125889
Subject(s) - medicine , adenocarcinoma , lung cancer , epidermal growth factor receptor , immunohistochemistry , oncology , carcinoma , malignancy , pathology , lung , cancer
Lung cancer is a highly aggressive malignancy causing high morbidity and mortality. An increasing incidence of lung cancer has been observed in India. Currently, the classification of lung carcinoma has gone beyond small cell lung carcinoma and non-small cell lung carcinoma (NSCLC). Precise subtyping of poorly differentiated NSCLC into adenocarcinoma and squamous cell carcinoma has a direct impact on patient management and prognosis. With this background, many molecules are under study for developing targeted therapies. Epidermal growth factor receptor (EGFR) is one such biomarker considered to be useful in targeted therapy for adenocarcinoma.