Open AccessReversible interstitial lung disease with prolonged use of nitrofurantoin: Do the benefits outweigh the risks?
Author(s) -
Akashdeep Singh,
Parminder Singh,
US Sidhu
Publication year - 2013
Publication title -
lung india
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 25
eISSN - 0974-598X
pISSN - 0970-2113
DOI - 10.4103/0970-2113.116271
Subject(s) - medicine , nitrofurantoin , honeycombing , interstitial lung disease , lung , disease , pulmonary fibrosis , lung disease , fibrosis , radiology , surgery , antibiotics , ciprofloxacin , microbiology and biotechnology , biology
We describe the case summary of a 70-year-old man diagnosed with interstitial lung disease due to prolonged nitrofurantoin therapy. Despite honeycombing confirmed by computed tomography of the thorax, symptoms and radiographic findings disappeared within 1 month after withdrawal of nitrofurantoin. The case highlights the fact that nitrofurantoin-induced lung disease may run a benign course and respond favorably despite radiographic evidence of established lung fibrosis (honey combing).