Open AccessHistological reclassification, histochemical characterization and c-kit immunoexpression in renal cell carcinoma
Author(s) -
P. Rekha,
S Rajendiran,
Shalinee Rao,
Sunil Shroff,
Leena Dennis Joseph,
D Prathiba
Publication year - 2008
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.42616
Subject(s) - chromophobe cell , medicine , clear cell , pathology , immunostaining , grading (engineering) , renal cell carcinoma , stain , clear cell carcinoma , staining , oncocytoma , immunohistochemistry , clear cell renal cell carcinoma , carcinoma , biology , ecology
Renal cell carcinoma is the most lethal of all urologic malignancies. Several parameters such as histological subtype, nuclear grade and TNM staging help in determining the prognosis and treatment options. A newer therapeutic modality has been suggested based on expression of c-kit antigen by the tumor cells. This study was designed to evaluate various histological parameters and correlate them with c-kit expression.