Open AccessPara aortic ganglioneuroma presenting as Cushing's syndrome
Author(s) -
Sudha Reddy,
G Purushottam,
K Pandurangarao,
PT Ravi Chander
Publication year - 2007
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.36725
Subject(s) - medicine , ganglioneuroma , metanephrines , histopathology , paraganglioma , dexamethasone , short stature , radiology , pathology , urinary system , neuroblastoma , genetics , biology , cell culture
We present a case of an eight-year-old female presenting with four months history of progressive weight gain, short stature, obesity, mild acanthosis, moon facies and buffalo hump. Biochemically, low-dose and high-dose Dexamethasone tests were not suppressible, ACTH was raised and 24h urinary metanephrines were normal. The CECT scan showed a 3cm paraganglioma. Tumor was excised via 11(th) rib transcostal approach and the mass was found arising from the sympathetic chain. Histopathology was suggestive of ganglioneuroma positive for ACTH immunostaining.