Open AccessA comparative study of intratumoral chemotherapy in advanced childhood common solid tumors
Author(s) -
Rajeev Rahi,
K Vijyendra,
Seema Sharma,
N C Aryya,
Ratnakar Shukla,
Satyajit Pradhan,
TB Singh,
A. N. Gangopadhyay
Publication year - 2007
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.36704
Subject(s) - neuroblastoma , chemotherapy , medicine , wilms' tumor , stage (stratigraphy) , solid tumor , response evaluation criteria in solid tumors , oncology , surgery , progressive disease , cancer , paleontology , genetics , biology , cell culture
Advanced and inoperable solid tumors in children are great killer despite aggressive multimodality treatment. Intravenous chemotherapy, due to high dose of drug given systemically, at times leads to abandonment of therapy due to systemic toxicities. To overcome this problem lots of studies are going on to explore alternative modes of giving anticancer drugs so as to decrease the systemic toxicities of the drugs and increase their therapeutic index at the same time.