
Penile lesion with inguinal adenopathy after intravesical Bacillus Calmette-Guerin instillation therapy
Author(s) -
Güven Aslan,
Can Sevinç,
Burçin Tuna,
Şermin Özkal,
Kutsal Yörükoğlu
Publication year - 2013
Publication title -
indian journal of urology/indian journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.333
H-Index - 30
eISSN - 1998-3824
pISSN - 0970-1591
DOI - 10.4103/0970-1591.109991
Subject(s) - medicine , penis , surgery , lesion , glans penis , urology , transitional cell carcinoma , lymph , carcinoma in situ , bladder cancer , carcinoma , cancer , pathology
Intravesical Bacillus Calmette-Guérin (BCG) is widely used as an adjuvant therapy in the treatment of non-muscle-invasive bladder cancer. BCG is generally well tolerated, though localized and systemic infectious complications may occur. Infection of the glans and inguinal adenopathy are rare local complications of intravesical BCG therapy. Traumatic urethral catheterization is one of the main causes. We report the case of a 75-year-old male who developed granulomatous balanitis and enlarged inguinal lymph nodes after five cycles of intravesical BCG treatment for transitional cell carcinoma of the bladder. Histology revealed giant cell granuloma. Oral antituberculous treatment was initiated with subsequent full recovery of penile lesions and adenopathy. Physicians who administer BCG must be familiar with the possible complications and their adequate management and should inform patients about the side-effects accordingly.