Open AccessAccuracy of indirect immunofluorescence on sodium chloride-split skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita
Author(s) -
Baoqi Yang,
Chong Wang,
Shengli Chen,
Xuechao Chen,
Guangjun Zhou,
Hongqing Tian,
Man Yu,
Dizhan Zhang,
Zhonghua Shi,
Furen Zhang
Publication year - 2011
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.86479
Subject(s) - iif , epidermolysis bullosa acquisita , bullous pemphigoid , antigen , sss* , direct fluorescent antibody , antibody , pathology , immunofluorescence , pemphigoid , medicine , radioimmunoassay , dermatology , indirect immunofluorescence , immunology
Previous reports have shown that indirect immunofluorescence (IIF) performed on sodium chloride-split skin (SSS) is helpful to differentiate epidermolysis bullosa acquisita (EBA) from bullous pemphigoid (BP). Antibodies of BP may bind to the epidermal side of SSS, while antibodies of EBA bind to the dermal side.