Langerhans cell histiocytosis: An uncommon presentation, successfully treated by thalidomide | Zendy

Safoura Shakoei | Zendy; Mohammad ShahidiDadras | Zendy; Mohammad Saeedi | Zendy; Azin Ayatollahi | Zendy

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Langerhans cell histiocytosis: An uncommon presentation, successfully treated by thalidomide

Author(s) -

Safoura Shakoei,

Mohammad ShahidiDadras,

Mohammad Saeedi,

Azin Ayatollahi

Publication year - 2011

Publication title -

indian journal of dermatology venereology and leprology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.514

H-Index - 45

eISSN - 0973-3922

pISSN - 0378-6323

DOI - 10.4103/0378-6323.84064

Subject(s) - langerhans cell histiocytosis , presentation (obstetrics) , medicine , dermatology , thalidomide , rare disease , histiocytosis , disease , surgery , pathology , multiple myeloma

Langerhans cell histiocytosis (LCH) is a rare disease and generally affects children under 15 years of age. Adult onset form and cutaneous features at presentation are uncommon. There are some options for treatment of the skin lesions of LCH such as topical and intralesional corticosteroid, nitrogen mustard, etc., which are not completely curative. Herein, we report a case of perianal LCH in a 20-year-old man with one-year history of recalcitrant well-demarcated, erythematous, and ulcerated plaque surrounding the anal orifice, with pain and difficulty in defecation that was successfully treated with thalidomide.

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