Open AccessNodular amelanotic melanoma
Author(s) -
Rashmi Nalamwar,
Vidya Kharkar,
Sunanda Mahajan,
Sidhhi Chikhalkar,
Uday Khopkar
Publication year - 2010
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - Uncategorized
Resource type - Journals
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.62972
Subject(s) - medicine , melanoma , biopsy , inguinal lymphadenopathy , amelanotic melanoma , wide local excision , thigh , soft tissue , reticular dermis , stage (stratigraphy) , dermis , metastasis , lymph , pathology , radiology , surgery , cancer , paleontology , cancer research , biology
We report a case of 65-year-old male patient who presented with multiple erythematous papules coalescing to form a nodular mass over posterior aspect of right thigh of six months duration. His general and systemic examinations were within normal range except for right inguinal lymphadenopathy. Biopsy from the lesion was done, which showed diffuse infiltrate of nests of atypical melanocytes extending upto reticular dermis. Malignant cells were positive for S100 and human melanin black 45(HMB 45). Hence, a diagnosis of amelanotic melanoma (AM)--Clarke level IV and TNM stage III was reached. MRI of involved leg showed fungating soft tissue mass in the posterolateral aspect of right thigh and metastatic right inguinal adenopathy. Fine needle aspiration cytology (FNAC) from the right inguinal nodes confirmed metastasis of melanoma. The patient was referred to oncosurgery department for further management.