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Atypical cutaneous lesions of penicillium marneffei infection as a manifestation of the immune reconstitution inflammatory syndrome after highly active antiretroviral therapy
Author(s) -
Lahari Saikia,
Reema Nath,
Dibya Jyoti Hazarika,
J Mahanta
Publication year - 2010
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.58678
Subject(s) - penicillium marneffei , medicine , penicillium , lesion , immune reconstitution inflammatory syndrome , dermatology , antiretroviral therapy , pathology , human immunodeficiency virus (hiv) , immunology , biology , viral load , coinfection , genetics
Penicillium marneffei infections normally manifest as molluscum contagiosum like skin lesion in HIV-infected persons. We report a case with verrucous lesions over nose and face due to Penicillium marneffei infection after HAART treatment. A 28-year-old man presented, after two weeks of HAART treatment, with multiple erythematous, scaly, papules and nodules with central necrosis predominantly in face and both extremities and scrotum. Microbiological investigations confirmed the diagnosis of Penicillium marneffei infection. This is perhaps the first case report with such manifestation due to Penicillium marneffei infection.

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