Open AccessCardio-pulmonary involvement in systemic sclerosis: A study at a tertiary care center
Author(s) -
Geetakiran Arakkal,
Sudha Rani Chintagunta,
Vasavilatha Chandika,
Sudha Vani Damarla,
Srinivas Manchala,
B Udaya Kumar
Publication year - 2017
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.198453
Subject(s) - medicine , bronchoalveolar lavage , pulmonary function testing , pulmonary hypertension , neutrophilia , interstitial lung disease , scleroderma (fungus) , high resolution computed tomography , microangiopathy , systemic scleroderma , dlco , pathology , cardiology , lung , diffusing capacity , disease , diabetes mellitus , lung function , inoculation , endocrinology
Systemic sclerosis is a multisystem disorder characterized by microangiopathy, dysregulation of the immune system and massive deposition of collagen in the connective tissue of the skin, blood vessels and various internal organs. Although the mortality from renal crises has dropped significantly due to the use of angiotensin-converting enzyme inhibitors, cardiac and pulmonary involvement accounts for significant morbidity and mortality. We studied 28 patients with systemic sclerosis at Gandhi Medical College and Hospital, Hyderabad, over a period of two years for cardiopulmonary involvement.