Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study | Zendy

Sujit J S Shanshanwal | Zendy; Rachita Dhurat | Zendy

Open Access

Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study

Author(s) -

Sujit J S Shanshanwal,

Rachita Dhurat

Publication year - 2016

Publication title -

indian journal of dermatology venereology and leprology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.514

H-Index - 45

eISSN - 0973-3922

pISSN - 0378-6323

DOI - 10.4103/0378-6323.188652

Subject(s) - finasteride , dutasteride , dihydrotestosterone , 5 alpha reductase inhibitor , medicine , urology , hair loss , testosterone (patch) , endocrinology , androgen , dermatology , prostate , cancer , hormone

Finasteride and dutasteride are inhibitors of the enzyme 5-alpha-reductase which inhibits the conversion of testosterone to dihydrotestosterone. Dutasteride inhibits both type I and type II 5-alpha-reductase while finasteride inhibits only the type II enzyme. As both isoenzymes are present in hair follicles, it is likely that dutasteride is more effective than finasteride.

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