Open AccessChlamydia trachomatis serovar G infection in a bisexual male with urethritis
Author(s) -
Jyoti Rawre,
Benu Dhawan,
Karnika Saigal,
Neena Khanna
Publication year - 2016
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.181470
Subject(s) - chlamydia trachomatis , serotype , virology , biology , genotype , restriction fragment length polymorphism , polymerase chain reaction , population , sexually transmitted disease , urethritis , chlamydia , microbiology and biotechnology , gene , genetics , medicine , human immunodeficiency virus (hiv) , environmental health , syphilis , urology
We report a case of Chlamydia trachomatis serovar G urogenital tract infection in a 33-year-old human immunodeficiency virus-1 (HIV-1) seropositive Indian bisexual male. This case highlights the emergence of a new serovar in India. The patient was tested positive for C. trachomatis by both cryptic plasmid and omp A gene polymerase chain reaction (PCR). On further characterization using polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) and omp A gene sequencing, the strain was found to be C. trachomatis serovar G. His spouse was also found to be infected with C. trachomatis serovar G. Phylogenetic analysis was performed on the clinical isolates obtained from both partners and were found to be identical to the isolates available in GenBank. The sexual network could not be traced further. Detection of a new genotype suggests importation of a new strain into the population probably by sexual contact with a person from a geographical area where the strain is common. Identifying circulating genotypes in the community can assist in developing strategies for improved sexually transmitted disease control.