Open AccessClinical efficacy of rituximab in the treatment of pemphigus: A retrospective study
Author(s) -
Vinod Sharma,
Neetu Bhari,
Somesh Gupta,
Kanika Sahni,
Neena Khanna,
M Ramam,
Gomathy Sethuraman
Publication year - 2016
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.174379
Subject(s) - medicine , rituximab , pemphigus , pemphigus vulgaris , azathioprine , prednisolone , pemphigus foliaceus , adverse effect , retrospective cohort study , rheumatoid arthritis , dapsone , gastroenterology , exacerbation , surgery , dermatology , immunology , autoantibody , disease , lymphoma , antibody
Pulsed corticosteroids have been used successfully for the management of pemphigus. However, prolonged use of glucocorticoids may be associated with adverse effects and some patients show a poor response to conventional therapy. Biologics have shown a promising role in such cases; however, there is limited data from the Indian subcontinent.