Open AccessA morphometric and immunohistochemical study of melanocytes in periorbital hyperpigmentation
Author(s) -
Dibyajyoti Boruah,
V Manu,
Ajay Malik,
Manas Chatterjee,
Biju Vasudevan,
V. Srinivas
Publication year - 2015
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.168327
Subject(s) - melanocyte , hyperpigmentation , epidermis (zoology) , immunohistochemistry , keratinocyte , melanin , basal (medicine) , dermatology , pathology , medicine , biology , anatomy , cell culture , cancer research , melanoma , insulin , genetics
An increase in number of melanocytes in the basal cell layer of the epidermis is an important feature in many disorders of hyperpigmentation. In this study, we attempted an objective evaluation of the linear density of melanocytes and keratinocytes, along with other epidermal characteristics, in periorbital hyperpigmentation using immunohistochemistry and morphometric techniques.