Open AccessComprehensive lipid tetrad index, atherogenic index and lipid peroxidation: Surrogate markers for increased cardiovascular risk in psoriasis
Author(s) -
S Sunitha,
Medha Rajappa,
Devinder Mohan Thappa,
Laxmisha Chandrashekar,
Malathi Munisamy,
G. Revathy,
M. Priyadarssini
Publication year - 2015
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.163734
Subject(s) - malondialdehyde , psoriasis , medicine , psoriasis area and severity index , lipoprotein , lipid profile , lipid peroxidation , cholesterol , endocrinology , dyslipidemia , oxidative stress , immunology , disease
Recently, the concept of "psoriatic march" has come to the fore, in which chronic cutaneous inflammation in psoriasis leads to systemic inflammation which, in conjunction with increased oxidative stress, triggers a cascade of events resulting in increased cardiovascular risk in patients with severe psoriasis. We, therefore, decided to study the levels of some biochemical cardiovascular risk markers: lipid peroxidation (malondialdehyde), lipoprotein (a), lipid indices and atherogenic index, in patients with psoriasis and their association with disease severity.