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Follicular Dowling Degos disease: A rare variant of an evolving dermatosis
Author(s) -
Sujay Khandpur,
Parul Verma,
Manoj K. Singh,
Saurabh Singh
Publication year - 2013
Publication title -
indian journal of dermatology venereology and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.120734
Subject(s) - reticulate , dermatology , follicular phase , pathogenesis , ichthyosis vulgaris , biology , phenotype , pathology , variable expression , hyperkeratosis , disease , medicine , genetics , gene , atopic dermatitis , botany , filaggrin
Dowling Degos disease is a rare, reticulate pigmentary disorder with variable phenotypic expression that manifests as hyperpigmented macules and reticulate pigmentary anomaly of the flexures. Many variants of this condition and its overlap with other reticulate pigmentary disorders have been reported in the literature. We present here two cases of DDD with follicular localization, both clinically and histologically. It was associated with ichthyosis vulgaris in one case. Follicular DDD is an uncommon variant of this evolving dermatosis. Our report supports the possible role for disordered follicular keratinisation in its pathogenesis.

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