Open AccessEpidermodysplasia verruciformis: An unusual malignant transformation
Author(s) -
Prachi G Agrawal,
Sunanda Mahajan,
Uday S Khopkar,
Vidya Kharkar
Publication year - 2013
Publication title -
indian journal of dermatology, venereology, and leprology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.514
H-Index - 45
eISSN - 0973-3922
pISSN - 0378-6323
DOI - 10.4103/0378-6323.104677
Subject(s) - epidermodysplasia verruciformis , malignant transformation , pityriasis , malignancy , dermatology , medicine , pathology , human papillomavirus
Epidermodysplasia verruciformis (EV) is a rare, life-long heritable disease caused due to a unique susceptibility to human papilloma virus. The disseminated verrucous lesions and pityriasis versicolor-like lesions persist from early childhood and can transform into a cutaneous malignancy in a fourth of patients. Malignant transformation into syringoid eccrine carcinoma (SEC) has been reported only once so far. SEC is an extremely invasive, rare, locally destructive, slowly growing adnexal tumor. We hereby report the association of EV with SEC in a 29-year-old male.