Childhood pemphigus vulgaris successfully treated with rituximab | Zendy

AmrinderJ Kanwar | Zendy; Keshavamurthy Vinay | Zendy; Gitesh U. Sawatkar | Zendy; Takashi Hashimoto | Zendy

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Childhood pemphigus vulgaris successfully treated with rituximab

Author(s) -

AmrinderJ Kanwar,

Keshavamurthy Vinay,

Gitesh U. Sawatkar,

Takashi Hashimoto

Publication year - 2012

Publication title -

indian journal of dermatology venereology and leprology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.514

H-Index - 45

eISSN - 0973-3922

pISSN - 0378-6323

DOI - 10.4103/0378-6323.100587

Subject(s) - rituximab , pemphigus vulgaris , pemphigus , medicine , dexamethasone , dermatology , refractory (planetary science) , immunology , lymphoma , physics , astrobiology

Pemphigus is a potentially fatal autoimmune epidermal bullous disorder. Rituximab is a novel therapy for the treatment of refractory pemphigus. However, there is limited clinical data on safety and efficacy of rituximab in pediatric age group. Herein, we report an 11-year-old boy of childhood pemphigus vulgaris who failed to respond to dexamethasone pulse therapy and was subsequently treated with rituximab and achieved complete remission.

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