Open AccessComparing touch imprint cytology, frozen section analysis, and cytokeratin immunostaining for intraoperative evaluation of axillary sentinel lymph nodes in breast cancer
Author(s) -
Akbar Safai,
Ali Razeghi,
Ahmad Monabati,
Negar Azarpira,
Abdolrasoul Talei
Publication year - 2012
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.97859
Subject(s) - medicine , frozen section procedure , h&e stain , sentinel lymph node , breast cancer , biopsy , cytokeratin , metastatic carcinoma , pathology , metastasis , axillary lymph nodes , breast carcinoma , lymph node , cancer , immunohistochemistry , carcinoma
Sentinel lymph node (SLN) biopsy has been applied to the management of breast carcinoma inorder to decrease postoperative complication and morbidity. Touch imprint cytology (TIC), frozen section (FS), scrape cytology, or combination of these methods are used as intraoperative diagnostic methods. However, the sensitivity of these intraoperative modalities for detecting metastatic disease in SLNs is not equivalent to permanent histopathologic examination as a gold standard method.