Open AccessHER 2 status in invasive breast cancer: Immunohistochemistry, fluorescence in-situ hybridization and chromogenic in-situ hybridization
Author(s) -
Hemlata Shirsat,
Sridhar Epari,
Tanuja Shet,
Rajani Bagal,
Ranjana Hawaldar,
Sangeeta Desai
Publication year - 2012
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.97855
Subject(s) - cish , chromogenic in situ hybridization , immunohistochemistry , fluorescence in situ hybridization , concordance , in situ hybridization , breast cancer , biology , medicine , pathology , cancer , oncology , gene , genetics , gene expression , chromosome
HER2/neu gene status in breast cancers can be evaluated by targeting protein and gene - immunohistochemistry (IHC) and fluorescence in-situ hybridization (FISH). Recent studies have shown chromogenic in-situ hybridization (CISH) as a relatively cheaper alternative.