Open AccessRole of C-erbB2 expression in gallbladder cancer
Author(s) -
Niraj Kumari,
Vinay K. Kapoor,
Narendra Krishnani,
Kamlesh Kumar,
Dinesh Kumar Baitha
Publication year - 2012
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.94862
Subject(s) - stage (stratigraphy) , malignancy , gallbladder cancer , immunohistochemistry , medicine , gallbladder , cancer , dysplasia , pathology , carcinoma , pathological , carcinogenesis , pathogenesis , gastroenterology , oncology , biology , paleontology
Gallbladder cancer (GBC) is a lethal malignancy presenting at an advanced stage. The pathogenesis is not well categorized, and surgery is the only treatment available at the early stage of the disease. There have been few reports on role of growth factor receptors in GBC. C-erbB2 is one such receptor whose over-expression is being explored in GBC as one of the factors involved in carcinogenesis and possible target for therapy.