Open AccessAntifungal susceptibility testing of Candida tropicalis biofilms against fluconazole using calorimetric indicator resazurin
Author(s) -
PM Punithavathy,
K Nalina,
Thangam Me
Publication year - 2012
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.94861
Subject(s) - resazurin , biofilm , fluconazole , microbiology and biotechnology , candida tropicalis , minimum inhibitory concentration , biology , antimicrobial , antifungal , chemistry , bacteria , genetics
C.tropicalis is an important cause of nosocomial infections particularly in immunocompromised patients. Infections caused by Candida spp. are often associated with biofilm formation on implanted medical devices or on epithelial cell surfaces. Phenotypic characteristics of sessile cells in biofilms are known to be different from those of their free-living, planktonic counterparts. Biofilm forming strains often show increased resistance to antimicrobial agents.