Hemophagocytic syndrome associated with Plasmodium falciparum infection | Zendy

JuliusXavier Scott | Zendy; PN Vinoth | Zendy; KAbilash Thomas | Zendy; S. Selvan | Zendy; DFebe Renjitha Suman | Zendy

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Hemophagocytic syndrome associated with Plasmodium falciparum infection

Author(s) -

JuliusXavier Scott,

PN Vinoth,

KAbilash Thomas,

S. Selvan,

DFebe Renjitha Suman

Publication year - 2011

Publication title -

indian journal of pathology and microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.217

H-Index - 31

eISSN - 0974-5130

pISSN - 0377-4929

DOI - 10.4103/0377-4929.85105

Subject(s) - hemophagocytosis , pancytopenia , hepatosplenomegaly , medicine , plasmodium falciparum , malaria , bone marrow , immunology , hypertriglyceridemia , pathology , disease , triglyceride , cholesterol

Hemophagocytic syndrome (HPS) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria is rarely reported to cause HPS. We report a case of an 11-month-old infant with fever, hepatosplenomegaly, pancytopenia, high serum ferritin, hypertriglyceridemia, and bone marrow hemophagocytosis, consistent with hemophagocytic syndrome. Gametocytes of plasmodium falciparum were identified on bone marrow aspiration. Rapid recovery was observed after treatment with antimalarials.

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