Open AccessHepatocyte growth factor profile with breast cancer
Author(s) -
H. A. El-Attar,
Manal Sheta
Publication year - 2011
Publication title -
indian journal of pathology and microbiology/indian journal of pathology and microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.217
H-Index - 31
eISSN - 0974-5130
pISSN - 0377-4929
DOI - 10.4103/0377-4929.85083
Subject(s) - medicine , breast cancer , hepatocyte growth factor , fibroadenoma , hepatocyte growth factor receptor , breast carcinoma , oncology , pathology , cancer , c met , receptor
The multifunctional hepatocyte growth factor (HGF) is the ligand of c-Met receptor; it plays important role in mammary differentiation. HGF-Met signaling is a critical downstream function of c-Src-Stat3 pathway in mammalian tumorigenesis.